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Clark’s Restaurant & Tavern

Family owned since 1946 and known for excellent Southern Cuisine; aged prime rib, Angus steaks, our signature hand-cut rib eye, fresh seafood, famous baked and fried chicken, fresh vegetables, homemade casseroles and desserts, great salads, sandwiches, and traditional country breakfasts.  Features a full-service pub.

Location: 8920 Hwy 6, Santee
Hours: Sun – Thurs 6 am -9 pm; Fri & Sat 6 am-10 pm
Phone: (803) 854-2101

Smoke'Em Barbecue Joint

A new favorite! By repetitive request, recently opened by local caterer and chef, this is not your usual southern BBQ place.  Stepping it up a notch with Burnt Belly Ends, Smoked Mozzarella Caprese, fresh Wedge Salad, Brisket Tacos, Smoked Wings and Nashville Hot Chicken.  Don’t skip the BBQ Egg Rolls!   Specials, Live Music and updates can be found on Smoke’Em Barbecue Joint Facebook page.

Location: 1636 Bridge Street, St. Matthews, SC
Hours:
Tuesday – Friday 11am-2pm & 5pm-9pm; Sunday Buffet 11am-2pm
Phone: (803) 542-3860

Sweatman’s BBQ

A local favorite! This whole hog bar-b-que is cooked fresh every week. The whole hogs are cooked 12-14 hours each night over hot coals from oak and pecan trees prepared during the week. While cooking, they are continuously basted with Sweatman’s secret mustard-based sauce.

Location: 1427 Eutaw Road, Holly Hill.
Hours: Open Friday and Saturday only. 11:30 am – 8:00 pm
Phone: (803) 496-1227

Captain’s Quarters

Seafood and variety restaurant located in the heart of Santee.  Enjoy shrimp and grits, fried seafood platter, and more!

Location: 9053 Hwy Six, Santee.
Hours: Open 7 days a week.
Phone: (803) 854-4695

Cork and Barrel

Cork and Barrel: Full service restaurant highlighting wine, bourbon, hand crafted tapas and signature dishes.

Located: 190 Plaza Circle Suite A, Santee.
Hours: Friday-Sunday 11am – 9pm.    Monday-Thursday 4pm-9pm.   Sunday Brunch.
Phone: (803) 857-2920

Thai House Restaurant

A modern interpretation of classic dishes using only fresh, high-quality ingredients.  Menu features amazing recipes from owners’ family gatherings. All items are made from scratch daily with hand selected ingredients to ensure each plate explodes with flavor.

Located: 9086 Old Number Six Hwy, Santee.
Hours: Open Wednesday – Monday.  Closed on Tuesdays.
Phone: (803) 854-9060

Take-out and dine-in.
Online ordering available. Offers catering and reservations for large parties with advance notice.

Tulio's Pizzeria & Restaurant

“Good to the Last Slice”  Hand-tossed crust, homemade sauce and all the toppings!  Fresh pizza, salads, pasta, wings and more.  Dine-in or Pick-up

Located: 705 Bass Drive, Santee
Hours: Open Tuesday-Saturday 11am-9pm.  Sunday 12noon-8pm.  Closed on Mondays.
Phone: (803)854-7021

Craig’s Place Deli

Craig’s Place Deli: New York-style deli featuring a variety of hot and cold sandwiches made with quality meats and cheeses and served by some of the nicest young people you’ll meet in Santee.  Enjoy sandwiches, soups, salads, and desserts with a smile.

Located: Hwy 6, Santee.
Hours: Open 7 days a week.
Phone: (803) 854-4601

Santee Steak & Seafood

Raw Market for hand-cut steaks and fresh seafood.    Shrimp, Crab/Crab Legs, Oysters (in season), Fish, Salmon, NY Strip, Prime Rib, Ribeye

Located: 9135 Old Number Hwy 6, Santee.
Hours: Raw Market Open 7 days a week, 11 am – 5 pm.  Food Truck Wed-Sat.  Dine-in Restaurant
Phone: (803) 854-9483

The Rotonda Restaurant

The Rotonda Restaurant: Friendly, a locally owned and operated with delicious southern comfort food, Sunday lunch buffet and catering available.

Located: 1550 Bass Drive, Santee.
Hours: Open 7 days week
Phone: (803) 854-9097

Santee Seafood Bistro

Santee Seafood Bistro:  Seafood & Southern comfort food.  Lunch, Dinner and Cocktails.  Dine-in, take-out, outside dining.

Located: 648 Bass Drive, Santee.
Hours: Open Tues- Sat (11:30AM-8:30PM) and Sunday (11:30 AM – 4:00 PM)
Phone: (803) 854-4840

Cedar Creek Tavern

(formerly Oasis Bar & Grill) A local venue with good food and good times. Drinks, karaoke, pool tables, and more.

Located: 8101 Old Hwy Six (west), Santee.
Hours: Under new ownership and renovation.  Opening Soon.
Phone: (803) 854-4321

Additional Local Favorites